Compritol® 888 ATO

Glyceryl dibehenate EP Glyceryl behenate NF/CR.P.

Gattefossé

Can be used in coating processes to provide a lipid barrier for the protection of sensitive active ingredients and to improve ingredient compatibility.

Key Features

  • Fine white powder of well-controlled particle size distribution with an indicative particle size of 50µm.
  • A high melting point lipid for use in modified release oral solid dosage forms (lipid matrix for sustained release, delayed release).
  • Effective lubricant for tablets and capsules.
  • Can be used in coating processes to provide a lipid barrier for the protection of sensitive active ingredients and to improve ingredient compatibility.
  • Chemically inert and highly compatible with other ingredients.


Safety of use is supported by toxicological data, GRAS status and precedence of use in approved pharmaceutical products.


Physical Form

  • Powder

Field of use

  • Human pharmaceutical products, veterinary products excluding food producing animals (EU)

Administration Route

  • Oral

Formulation techniques and dosage forms

  • Forms lipid matrix for modified release tablets produced by direct compression.
  • Lubricant for tablets produced by direct compression.
  • Suitable for use in melt processing techniques: spray cooling /prilling, hot melt coating and melt extrusion techniques for capsule filling, tabletting, sachets and suspensions etc
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