Gelucire® 50/13

Stearoyl macrogol / polyoxyl 32 glycerides

Gattefossé

A non-ionic, water dispersible surfactant composed of well-characterized PEG-esters, a small glyceride fraction and free PEG.

Key Features

  • A non-ionic, water dispersible surfactant composed of well-characterized PEG-esters, a small glyceride fraction and free PEG.
  • Able to self-emulsify on contact with aqueous media forming a fine dispersion ie. microemulsion (SMEDDS).
  • Solubilizer/wetting agent: surfactive power improves the solubility and wettability of active pharmaceutical ingredients in vitro and in vivo.
  • Bioavailability enhancer: improved in vivo drug solubilization facilitates absorption.
  • Good thermoplasticity for use as a binder in melt processes.

Safety of use is supported by toxicological data and precedence of use in approved pharmaceutical products.


Physical Form

  • Semi-solid block

Hydrophilic-Lipophilic Balance (HLB)

  • 11

Field of use

  • Human pharmaceutical products, veterinary products excluding food producing animals (EU)

Administration Route

  • Oral

Formulation techniques and dosage forms

  • Use in melt processing techniques: melt granulation (thermoplastic pelletization) and melt extrusion techniques for capsule filling, tabletting, sachets etc.
  • Suitable for hard gelatin capsule molding.
  • Suitable for adsorption onto neutral carrier powders for use in tablets, capsule filling and sachets.

This product belongs to